Denise Rable M.D., F.A.C.S.

10900 Hefner Pointe Dr
Suite 505
Oklahoma City, OK 73120

8 am - 5 pm Monday -Friday

Office: (405) 552-0400
Fax: (405) 752-4251

News & Events

•7-15-2016• Tiny Radioactive Seed Makes a Big Impact in Breast Cancer Surgery

OKLAHOMA CITY (July, 2016) – Lakeside Women’s Hospital, part of the INTEGRIS network, is the first facility in Oklahoma to offer a new, more patient-friendly approach to pinpointing and removing very small breast cancers.

The innovative procedure is called radioactive seed localization. Using a mammogram or ultrasound for guidance, Charles Groves, M.D., a breast radiologist and medical director of the INTEGRIS Comprehensive Breast Center of Oklahoma, uses a thin needle to place a tiny metal seed into the breast to mark the exact location of the cancer. The implanted seed contains a small amount of radiation that helps the surgeon locate the area of abnormal tissue during surgery when it is too small to be seen or felt by hand.

“Until now, patients with such small breast cancers were required to undergo a procedure called breast needle localization, in which we would insert a wire into the breast to map the location of the cancer,” says Groves. “The wire remained in the breast, projecting out of the skin for several hours until the surgery. The wire was used to guide the surgeon during the operation.”

With the RSL approach, as it is called, the seed is implanted and the patient is allowed to go home and rest comfortably until their surgery date later that week. Denise Rable, M.D., Integris Breast Surgical Oncologist at Lakeside, uses a handheld radiation detection device to zero in on the seed and precisely navigate to the location of the cancer, which is removed along with the seed during the operation. Removal of appropriate breast tissue as well as the radioactive seed is confirmed with state of the art intraoperative 3D imaging of the specimen. After the procedure, no radioactivity remains in the body.

“Studies suggest that radioactive seed localization can provide a level of accuracy not typically found with the wire method, which in turn allows for a more-precise removal of small breast cancers,” says Rable. “It can reduce the need to have a second surgery due to incomplete removal of the abnormal tissue, and helps to preserve healthy tissue. Additionally, patient comfort and convenience are markedly improved with radioactive seed localization when compared to wire localization procedure.”

The radioactive seed is strictly used for tumor marking. It does not replace radiation or chemotherapy as a method of treating the cancer.

• 2-17-2015 • Dr. Denise Rable has been appointed the new Director of Breast Surgery for the Integris Health System.
Dr. Rable has joined the largest Health Network in Oklahoma, Integris Health. She is very excited about the new opportunity to develop a world class breast health program with Integris Health. Dr. Rable's office is near the Lake side Women's Hospital adjacent to Lake Hefner in Oklahoma City. 
Integris Health ranks as one of the top 25 health care systems in the US and features the best hospital in Oklahoma City according to US News & World Reports.

• 10-1-2014 • Oklahoma Top Doctor For the seventh year
Dr. Denise Rable has been selected an Oklahoma Top Doctor. The 2014 Top Doctors list, compiled by Castle Connolly, publishers of America’s Top Doctors, features doctors that have been judged by their peers to be the top in their profession. Dr. Rable was a highlighted physician in the June 2012 issue of Oklahoma Magazine.

October is Breast Cancer Awareness Month
, where millions of people across the country will be participating in events and showing their support to raise awareness of the disease. While many are certainly aware of and suffer from breast cancer, there is a large amount of the population that isn't aware of how to prevent and fight the disease.

Here's how you can support Breast Cancer Awareness in October.

1. Take the PLEDGE!

While many people are well affiliated with breast cancer, some still don't know the proper steps to prevent and monitor their chances at getting the disease. The PLEDGE is a six step system women are encouraged to learn more about breast cancer and spread their knowledge and awareness to friends and family.

  • PREVENTION: Ask my doctor what steps I can take that could reduce my risk of breast cancer.

  • LEARNING: Arm myself with knowledge about my own risks.

  • EXAMINATION: With my doctor, find out when I should get screened for breast cancer, and how often.

  • DENSITY: Have a conversation with my doctor to see if I have "dense" breasts, and which screening approach is right for me.

  • GENETICS: Discuss with my doctor my family history - both mom's and dad's side - of breast cancer, to see what it might mean for my level of risk.

  • EDUCATE - Once I've put these steps into action, "pay it forward" by encouraging friends and family to do it as well.
2. Participate in a Breast Cancer Awareness event in your local community.

Race for the Cure Tulsa 9-27-2014 @ ONEOK

Race for the Cure Oklahoma City  10-18 2014 @ The Myriad Botanical Gardens

3. Get familiar with facts and figures of breast cancer.

Before you participate in one of these events, make sure you take a look over these important and lesser-known Breast Cancer facts, provdied by the ABC News Medical Unit.

  • Over the course of a lifetime, a woman living in the United States has a 2.7% chance of dying of breast cancer - a 12.3% lifetime risk of being diagnosed with it.
    Breast Cancer Facts & Figures 2013-2014. American Cancer Society.

  • Breast cancer is the second leading cause of cancer deaths among women in the U.S. (lung cancer is #1).
    Breast Cancer Facts & Figures 2013-2014. American Cancer Society.

  • There are 2.9 million breast cancer survivors in the U.S. today - more people than the population of Chicago.
    Siegel R, DeSantis C, Virgo K, et al. Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin. Jul-Aug 2012; 62 (4): 220-41.

  • Statistics are not destiny -- your individual chance of survival after 5 years may be more than 89%.
    Breast Cancer Facts & Figures 2013-2014. American Cancer Society.

  • Mammography was first used in 1969 when the first specialized X-ray unit for breast imaging was developed.
    Brown, Zora K. and Karl K. Boatman, MD. 2009. 100 Questions and Answers about Breast Cancer. 3rd ed. Boston, MA: Jones and Bartlett Publishers.

  • As little as two and a half hours per week of brisk walking can reduce the risk of breast cancer by as much as 18%.
    McTiernan A, Kooperberg C, White E, et al. Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study. JAMA. 2003; 290:1331-1336.

  • It has been estimated that if every woman over the age of 50 had her yearly mammogram, breast cancer deaths in this age group could drop by 25% or more.
    Breast Cancer Facts and Figures: 2009-2010." American Cancer Society. 2009.

  • Women who consume more than 3 alcoholic beverages per day are 51% more likely to be diagnosed with breast cancer than women who do not drink.
    Hamajima N, Hirose K, Tajima K, et al. Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. British Journal of Cancer 2002;87(11):1234-1245.

  • Breastfeeding not only helps babies, it's been shown to reduce breast cancer- the more months you breastfeed, the greater the benefit.
    Collaborative Group on Hormonal Factors in Breast Cancer.
    Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease. Lancet. Jul 20 2002;360(9328):187-95.

  • When you look at your "family history" of breast cancer, your father's side is as important as your mother's.
    Brown, Zora K. and Karl K. Boatman, MD. 2009. 100 Questions and Answers about Breast Cancer. 3rd ed. Boston, MA: Jones and Bartlett Publishers.
4-1-2012 Testing for Hereditary Breast Cancer Gene Available
Dr. Rable is currently administering the BRACAnalysis® test which assesses a woman's risk of developing breast or ovarian cancer based on detection of mutations in the BRCA1 and BRCA2 genes. This test has become the standard of care in identification of individuals with hereditary breast and ovarian cancer and may be reimbursed by insurance when medically indicated. Please call Dr. Rable's office or visit the myriadtests.com website to learn more about inherited breast and ovarian cancer.