Denise Rable M.D., F.A.C.S.

10900 Hefner Pointe Dr
Suite 505
Oklahoma City, OK 73120

8 am - 5 pm Monday -Friday

Office: 405-552-0400

Fax: 405-752-4251

News & Events
Oklahoma City (2018) - Oklahoma Top Doctor For the eleventh year
Dr. Denise Rable has been selected an Oklahoma Top Doctor. The 2018 Top Doctors list, compiled by Castle Connolly, publishers of America’s Top Doctors, features doctors that have been judged by their peers to be the top in their profession. Dr. Rable was a highlighted physician in the June 2012 issue of Oklahoma Magazine.

Oklahoma City (July 21, 2016) - Lakeside Women’s Hospital, part of the INTEGRIS network, is the first facility in Oklahoma to offer a new, more patient-friendly approach to pinpointing and removing very small breast cancers.The innovative procedure is called radioactive seed localization. Using a mammogram or ultrasond for guidance, Charles Groves, M.D., a breast radiologist and medical director of the INTEGRIS Comprehensive Breast Center of Oklahoma, uses a thin needle to place a tiny metal seed into the breast to mark the exact location of the cancer. The implanted seed contains a small amount of radiation that helps the surgeon locate the area of abnormal tissue during surgery when it is too small to be seen or felt by hand.

“Until now, patients with such small breast cancers were required to undergo a procedure called breast needle localization, in which we would insert a wire into the breast to map the location of the cancer,” says Groves. “The wire remained in the breast, projecting out of the skin for several hours until the surgery. The wire was used to guide the surgeon during the operation.”

With the RSL approach, as it is called, the seed is implanted and the patient is allowed to go home and rest comfortably until their surgery date later that week. Denise Rable, M.D., an INTEGRIS breast surgical oncologist at Lakeside, uses a handheld radiation detection device to zero in on the seed and precisely navigate to the location of the cancer, which is removed along with the seed during the operation. Removal of appropriate breast tissue as well as the radioactive seed is confirmed with state of the art intraoperative 3D imaging of the specimen. After the procedure, no radioactivity remains in the body.

“Studies suggest that radioactive seed localization can provide a level of accuracy not typically found with the wire method, which in turn allows for a more-precise removal of small breast cancers,” says Rable. “It can reduce the need to have a second surgery due to incomplete removal of the abnormal tissue, and helps to preserve healthy tissue. Additionally, patient comfort and convenience are markedly improved with radioactive seed localization when compared to wire localization procedure.”

The radioactive seed is strictly used for tumor marking. It does not replace radiation or chemotherapy as a method of treating the cancer.

Oklahoma City (2-17-2015) - Dr. Denise Rable has been appointed the new Director of Breast Surgery for the Integris Health System.
Dr. Rable has joined the largest Health Network in Oklahoma, Integris Health. She is very excited about the new opportunity to develop a world class breast health program with Integris Health. Dr. Rable's office is near the Lake side Women's Hospital adjacent to Lake Hefner in Oklahoma City. Integris Health ranks as one of the top 25 health care systems in the US and features the best hospital in Oklahoma City according to US News & World Reports.

Oklahoma City (4-1-2012) - Testing for Hereditary Breast Cancer Gene Available
Dr. Rable is currently administering the BRACAnalysis® test which assesses a woman's risk of developing breast or ovarian cancer based on detection of mutations in the BRCA1 and BRCA2 genes. This test has become the standard of care in identification of individuals with hereditary breast and ovarian cancer and may be reimbursed by insurance when medically indicated. Please call Dr. Rable's office or visit the myriadtests.com website to learn more about inherited breast and ovarian cancer.

October is Breast Cancer Awareness Month, where millions of people across the country will be participating in events and showing their support to raise awareness of the disease. While many are certainly aware of and suffer from breast cancer, there is a large amount of the population that isn't aware of how to prevent and fight the disease. Here's how you can support Breast Cancer Awareness in October.

Take the PLEDGE!
While many people are well affiliated with breast cancer, some still don't know the proper steps to prevent and monitor their chances at getting the disease. The PLEDGE is a six step system women are encouraged to learn more about breast cancer and spread their knowledge and awareness to friends and family.
  • PREVENTION: Ask my doctor what steps I can take that could reduce my risk of breast cancer.
  • LEARNING: Arm myself with knowledge about my own risks.
  • EXAMINATION: With my doctor, find out when I should get screened for breast cancer, and how often.
  • DENSITY: Have a conversation with my doctor to see if I have "dense" breasts, and which screening approach is right for me.
  • GENETICS: Discuss with my doctor my family history - both mom's and dad's side - of breast cancer, to see what it might mean for my level of risk.
  • EDUCATE - Once I've put these steps into action, "pay it forward" by encouraging friends and family to do it as well.